Murphy Lab Researchers Identify Novel Approach to Create Red Blood Cells, Platelets In Vitro

A study led by Boston University School of Medicine has identified a novel approach to create an unlimited number of human red blood cells and platelets in vitro. In collaboration with Boston University School of Public Health (BUSPH) and Boston Medical Center (BMC), the researchers differentiated induced pluripotent stem (iPS) cells into these cell types, which are typically obtained through blood donations. This finding could potentially reduce the need for blood donations to treat patients requiring blood transfusions and could help researchers examine novel therapeutic targets to treat a variety of diseases, including sickle cell disease.  Published online in the journal Blood, the study was led by George J. Murphy, PhD, assistant professor of medicine at BUSM and co-director of the Center for Regenerative Medicine (CReM) at Boston University and BMC and performed in collaboration with David Sherr, PhD, a professor in environmental health at BUSM and BUSPH.

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Richard presents his work at the International Symposium on Amyloidosis in Kumamoto, Japan

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Murphy lab publishes an improved protocol for generating HSPCs from iPSCs in Stem Cells

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Richard is awarded a Junior Researcher Travel Award for the XVIth International Symposium on Amyloidosis in Kumamoto, Japan

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Kim is awarded an ASH Abstract Achievement Award for her work submitted to the 2017 ASH Meeting

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Congratulations to Spoorthi who begins her medical school training at BU’s 2017 white coat ceremony!

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Boston Magazine features the CReM and the Murphy lab

Blood tube at the microbiology laboratory

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Murphy Lab and the CReM Featured on CBS Boston with Dr. Mallika Marshall: Brewing Blood

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Richard’s poster wins first prize at the 2017 BU-CTSI Annual Translational Research Symposium!

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Drs. Murphy, Mostoslavsky and Steinberg create the world’s largest sickle cell disease-specific iPSC library

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Dr. Murphy awarded Scholar Award from the National Blood Foundation

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