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The Murphy Laboratory
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Welcome to the Murphy Lab
Mission and Vision
What is aging?
What are iPSCs?
Research
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Centenarian iPSCs
iPSC-based modeling of resilience
The 100-year-old neuron
Controlled induction of epigenetic age
Clinical trial in a test tube
Publications
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George J. Murphy
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Publications
Fine-Tuning Mybl2 Is Required for Proper Mesenchymal-to-Epithelial Transition during Somatic Reprogramming
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Publications
A library of ATTR amyloidosis patient-specific induced pluripotent stem cells for disease modelling and in vitro testing of novel therapeutics
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Publications
Induced pluripotent stem cell–based mapping of b-globin expression throughout human erythropoietic development
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Publications
Notch and Aryl Hydrocarbon Receptor Signaling Impact Definitive Hematopoiesis from Human Pluripotent Stem Cells
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Publications
A long noncoding RNA from the HBS1L-MYB intergenic region on chr6q23 regulates human fetal hemoglobin expression
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Publications
A phased SNP-based classification of sickle cell anemia HBB haplotypes
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Publications
Dioxins and related environmental contaminants increase TDP-43 levels
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Publications
A Comprehensive, Ethnically Diverse Library of Sickle Cell Disease-Specific Induced Pluripotent Stem Cells
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Publications
A candidate transacting modulator of fetal hemoglobin gene expression in the Arab—Indian haplotype of sickle cell anemia
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Publications
Genome Editing of the CYP1A1 Locus in iPSCs as a Platform to Map AHR Expression throughout Human Development
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