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The Murphy Laboratory
About us
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Welcome to the Murphy Lab
Mission and Vision
What is aging?
What are iPSCs?
Research
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Centenarian iPSCs
iPSC-based modeling of resilience
The 100-year-old neuron
Controlled induction of epigenetic age
Clinical trial in a test tube
Publications
People
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George J. Murphy
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Biography
Podcast
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Publications
Amelioration of emphysema in mice through lentiviral transduction of long-lived pulmonary alveolar macrophages
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Publications
Excision of reprogramming transgenes improves the differentiation potential of iPS cells generated with a single excisable vector
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Publications
Induced pluripotent stem cell generation using a single lentiviral stem cell cassette
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Publications
The scl +18/19 stem cell enhancer is not required for hematopoiesis: identification of a 5′ bifunctional hematopoietic-endothelial enhancer bound by Fli-1 and Elf-1
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Publications
Exogenous control of mammalian gene expression via modulation of translational termination
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Publications
Manipulation of mouse hematopoietic progenitors by specific retroviral infection
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Publications
Characterization of Mpl mutants using primary megakaryocyte-lineage cells from mpl2/2 mice: a new system for Mpl structure–function studies
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Publications
Primary Megakaryocytes Reveal a Role for Transcription Factor NF-E2 in Integrin aIIbb3 Signaling
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A model for studying megakaryocyte development and biology
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