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The Murphy Laboratory
About us
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Welcome to the Murphy Lab
Mission and Vision
What is aging?
What are iPSCs?
Research
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Centenarian iPSCs
iPSC-based modeling of resilience
The 100-year-old neuron
Controlled induction of epigenetic age
Clinical trial in a test tube
Publications
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George J. Murphy
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Biography
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Publications
The lung is a megakaryocyte outpost that can defend against thrombocytopenic attack.
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Publications
Centenarian/Exceptional Longevity (EL) iPSC Bank
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Publications
De novo hematopoiesis from the fetal lung
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Publications
Intertumoral lineage diversity and immunosuppressive transcriptional programs in well-differentiated gastroenteropancreatic neuroendocrine tumors
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Publications
Multi-modal profiling of peripheral blood cells across the human lifespan reveals distinct immune cell signatures of aging and longevity
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Publications
Notch activation during early mesoderm induction modulates emergence of the T/NK cell lineage from human iPSCs
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Publications
The protein organization of a red blood cell
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Publications
Non-coding RNA LEVER sequestration of PRC2 can mediate long range gene regulation
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Publications
Pharmacologic induction of PGC-1a stimulates fetal haemoglobin gene expression
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Publications
Comprehensive phenotyping of hematopoietic stem and progenitor cells in the human fetal liver
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