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The Murphy Laboratory
About us
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Welcome to the Murphy Lab
Mission and Vision
What is aging?
What are iPSCs?
Research
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Centenarian iPSCs
iPSC-based modeling of resilience
The 100-year-old neuron
Controlled induction of epigenetic age
Clinical trial in a test tube
Publications
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George J. Murphy
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Biography
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Publications
The role of the aryl hydrocarbon receptor in the development of cells with the molecular and functional characteristics of cancer stem-like cells
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Publications
Insulin-like growth factor 2 modulates murine hematopoietic stem cell maintenance through upregulation of p57
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Publications
Emergence of a stage-dependent human liver disease signature with directed differentiation of alpha-1 antitrypsin-deficient iPS cells
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Publications
Stem cells, megakaryocytes, and platelets
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Publications
ALS-linked mutations enlarge TDP-43-enriched neuronal RNA granules in the dendritic arbor
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Publications
Induced pluripotent stem cell modeling of multisystemic, hereditary transthyretin amyloidosis
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Publications
The aryl hydrocarbon receptor directs hematopoietic progenitor cell expansion and differentiation
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Publications
Generation of human induced pluripotent stem cells from peripheral blood using the STEMCCA lentiviral vector
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Publications
Mouse ES and iPS cells can form similar definitive endoderm despite differences in imprinted genes
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Publications
Generation of transgene-free lung disease-specific human induced pluripotent stem cells using a single excisable lentiviral stem cell cassette
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